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Advancing knowledge and Care in Hypoglycaemia
The International Hypoglycaemia Study Group is a not-for-profit global collaboration of experts in the field of diabetes and endocrinology who work to improve understanding, prevention and management of hypoglycaemia
Types of hypoglycaemia
Mild hypoglycaemia
- Causes discomfort
- Resolves promptly with prompt ingestion of carbohydrates
- Though named “mild”, it can still significantly impact quality of life
Severe hypoglycaemia
- Causes impairment of cognitive function
- Can lead to loss of consciousness
- Can be life threatening1
Nocturnal hypoglycaemia
- Occurs during sleep and is often asymptomatic
- Repeated exposure can disrupt the body’s natural blood sugar regulation system, leading to serious clinical consequences
To align hypoglycaemia terminology in clinical trials and encourage appropriate responses in clinical practice, the IHSG has developed the following definitions:1
Level 1
A glucose alert value of 3.9 mmol/L (70 mg/dL) or less. This often doesn’t need to be reported routinely, depending on the purpose of the clinical study.
Level 2
A glucose alert value of <3.0 mmol/L (<54 mg/dL) is sufficiently low and indicates serious, clinically important hypoglycaemia.
Level 3
As defined by the ADA, severe hypoglycaemia indicates severe cognitive impairment requiring external assistance for recovery.
Learn everything you need to know about low blood sugar
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